Professor David Grayden

Research Interests

  • Bionic Ear (Speech processing, bionics, neuroengineering)
  • Bionic Eye (Vision processing, bionics, neuroengineering)
  • Brain-Machine Interfaces (Brain-computer interfaces, bionics, neuroengineering)
  • Computational Neuroscience (Neural modelling, neural learning, neural dynamics, neuroengineering)
  • Epilepsy (Prediction of seizures, seizure control, neuroengineering)

Personal webpage


Professor David Grayden is Deputy Head (Academic) of the Department of Electrical and Electronic Engineering and Leader of the Bionics Laboratory in the Centre for Neural Engineering, The University of Melbourne .

Prof Grayden's main research interests are in understanding how the brain processes information, how best to present information to the brain using medical bionics, such as the bionic ear and bionic eye, and how to record information from the brain, such as for brain-machine interfaces. He is also conducting research in epileptic seizure prediction and electrical stimulation to prevent or stop epileptic seizures. He has research linkages in Australia with Cochlear Limited, the Bionics Institute, St Vincent's Hospital Melbourne, Royal Melbourne Hospital, NICTA, University of South Australia, Florey Institute for Neuroscience and Mental Health.  He also has international research linkages with Illmenau University of Technology, Germant and University of Maryland, USA.  He supervises a number of postdoctoral researchers and PhD and Research Masters students.

Prof Grayden teaches in the Bioengineering and Biomedical Engineering programs.  He teaches in the subjects: BioDesign Innovation, Neural Information Processing, Biosystems Design, and Biomedical Engineering Design Project.  He also contributes to the Neuroscience Research Training course modules.

Research interests:
Computational Neuroscience
Audition, Speech and Bionic Ear Design
Vision and Bionic Eye Design
Brain-Machine Interfaces

Recent Publications

  1. Maturana M, Maturana MI, Apollo NV, Hadjinicolaou AE, Garrett D, Garrett DJ, Cloherty S, Cloherty SL, Kameneva T, Grayden D, Ibbotson M, Ibbotson MR, Meffin H. A Simple and Accurate Model to Predict Responses to Multi-electrode Stimulation in the Retina. PLOS COMPUTATIONAL BIOLOGY. Public Library of Science. 2016, Vol. 12, Issue 4.
  2. Ahmadizadeh S, Nesic D, Grayden D, Freestone D. Analytic synchronization conditions for a network of Wilson and Cowan oscillators. Proceedings of the IEEE Conference on Decision and Control. 2016, Vol. 2016-February.
  3. Saha S, Greferath U, Vessey K, Grayden D, Burkitt A, Fletcher E. Changes in ganglion cells during retinal degeneration. Neuroscience. Pergamon-Elsevier Science. 2016, Vol. 329.
  4. Cook M, Karoly P, Freestone D, Himes D, Leyde K, Berkovic S, O'Brien T, Grayden D, Boston R. Human focal seizures are characterized by populations of fixed duration and interval. EPILEPSIA. Blackwell Science. 2016, Vol. 57, Issue 3.
  5. Karoly P, Freestone D, Boston R, Grayden D, Himes D, Leyde K, Seneviratne U, Berkovic S, O'Brien T, Cook M. Interictal spikes and epileptic seizures: their relationship and underlying rhythmicity. BRAIN. Oxford University Press. 2016, Vol. 139, Issue 4.
  6. Erfanian Saeedi N, Blamey PJ, Burkitt A, Grayden D. Learning Pitch with STDP: A Computational Model of Place and Temporal Pitch Perception Using Spiking Neural Networks. PLOS COMPUTATIONAL BIOLOGY. Public Library of Science. 2016, Vol. 12, Issue 4.
  7. Oxley T, Opie N, John S, Rind GS, Ronayne SM, Wheeler TL, Judy JW, McDonald AJ, Dornom A, Lovell T, Steward C, Garrett DJ, Moffat BA, Lui EH, Yassi N, Campbell B, Wong YT, Fox KE, Nurse ES, Bennett IE, Bauquier S, Liyanage KA, Van Der Nagel NR, Perucca P, Ahnood A, Gill KP, Yan B, Churilov L, French C, Desmond PM, Horne MK, Kiers L, Prawer S, Davis S, Burkitt A, Mitchell PJ, Grayden D, May C, O'Brien T. Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity. NATURE BIOTECHNOLOGY. Nature Publishing Group. 2016, Vol. 34, Issue 3.
  8. Kameneva T, Maturana MI, Hadjinicolaou AE, Cloherty SL, Ibbotson MR, Grayden D, Burkitt A, Meffin H. Retinal ganglion cells: mechanisms underlying depolarization block and differential responses to high frequency electrical stimulation of ON and OFF cells. JOURNAL OF NEURAL ENGINEERING. Institute of Physics Publishing. 2016, Vol. 13, Issue 1.
  9. Wong Y, Wong YT, Halupka K, Kameneva T, Cloherty SL, Grayden D, Burkitt A, Meffin H, Shivdasani MN. Spectral distribution of local field potential responses to electrical stimulation of the retina. JOURNAL OF NEURAL ENGINEERING. Institute of Physics Publishing. 2016, Vol. 13, Issue 3.
  10. Nurse E, Karoly P, Grayden D, Freestone D. A Generalizable Brain-Computer Interface (BCI) Using Machine Learning for Feature Discovery. PLOS ONE. Public Library of Science. 2015, Vol. 10, Issue 6.
  11. Spencer M, Nayagam D, Clarey JC, Paolini A, Meffin H, Burkitt A, Grayden D. Broadband Onset Inhibition Can Suppress Spectral Splatter in the Auditory Brainstem. PLOS ONE. Public Library of Science. 2015, Vol. 10, Issue 5.
  12. Aram P, Freestone D, Cook M, Kadirkamanathan V, Grayden D. Model-based estimation of intra-cortical connectivity using electrophysiological data. NEUROIMAGE. Academic Press. 2015, Vol. 118.
  13. Gao X, Grayden D, McDonnell MD. Modeling electrode place discrimination in cochlear implants: Analysis of the influence of electrode array insertion depth. International IEEE/EMBS Conference on Neural Engineering, NER. 2015, Vol. 2015-July.
  14. Nurse E, Freestone D, Oxley T, Ackland D, Vogrin S, Murphy M, O'Brien T, Cook M, Grayden D. Movement related directional tuning from broadband electrocorticography in humans. International IEEE/EMBS Conference on Neural Engineering, NER. 2015, Vol. 2015-July.
  15. Hersbach A, Grayden D, Fallon J, McDermott H. Perceptual effect of reverberation on multi-microphone noise reduction for cochlear implants. ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings. 2015, Vol. 2015-August.

David Grayden

Level: 02 Room: 229
Electrical and Electronic Engineering, Parkville
University of Melbourne
3010 Australia

T: +61 3 90353796
F: +61 3 83447422

View a full list of publications on the University of Melbourne’s ‘Find An Expert’ profile