Professor David Grayden

Research Interests

  • Bionic Ear (Speech processing, bionics, neuroengineering)
  • Bionic Eye (Vision processing, bionics, neuroengineering)
  • Brain-Machine Interfaces (Brain-computer interfaces, bionics, neuroengineering)
  • Computational Neuroscience (Neural modelling, neural learning, neural dynamics, neuroengineering)
  • Epilepsy (Prediction of seizures, seizure control, neuroengineering)

Personal webpage


Professor David Grayden is Head of the Department of Biomedical Engineering, Melbourne School of Engineering and Leader of the Bionics Laboratory in the Centre for Neural Engineering, The University of Melbourne.

Prof Grayden's main research interests are in understanding how the brain processes information, how best to present information to the brain using medical bionics, such as the bionic ear and bionic eye, and how to record information from the brain, such as for brain-machine interfaces. He is also conducting research in epileptic seizure prediction and electrical stimulation to prevent or stop epileptic seizures, and in electrical stimulation of the vagus nerve to control inflammatory bowel disease. He has research linkages with the Bionics Institute, St Vincent's Hospital Melbourne, Royal Melbourne Hospital, University of South Australia, Florey Institute for Neuroscience and Mental Health, and University of Maryland, USA.

Prof Grayden teaches in the Bioengineering and Biomedical Engineering programs.  He teaches in the subjects: BioDesign Innovation, Biosystems Design, and Biomedical Engineering Design Project.  He also contributes to the Neuroscience Research Training course modules.

Research interests:
Computational Neuroscience
Audition, Speech and Bionic Ear Design
Vision and Bionic Eye Design
Brain-Machine Interfaces

Recent Publications

  1. Yoo P, John S, John SE, Farquharson S, Cleary J, Wong YT, Ng A, Mulcahy C, Grayden D, Ordidge R, Opie N, Opie NL, O'Brien T, O'Brien TJ, Oxley T, Moffat B. 7T-fMRI: Faster temporal resolution yields optimal BOLD sensitivity for functional network imaging specifically at high spatial resolution. NeuroImage. Academic Press. 2017.
  2. Erfaniansaeedi N, Blamey P, Burkitt A, Grayden D. An integrated model of pitch perception incorporating place and temporal pitch codes with application to cochlear implant research. HEARING RESEARCH. Elsevier Science. 2017, Vol. 344.
  3. Halupka K, Shivdasani M, Cloherty S, Grayden D, Wong Y, Burkitt A, Meffin H. Prediction of cortical responses to simultaneous electrical stimulation of the retina. JOURNAL OF NEURAL ENGINEERING. Institute of Physics Publishing. 2017, Vol. 14, Issue 1.
  4. O'Sullivan-Greene E, Kuhlmann L, Nurse ES, Freestone DR, Grayden D, Cook M, Burkitt A, Mareels I. Probing to Observe Neural Dynamics Investigated with Networked Kuramoto Oscillators. INTERNATIONAL JOURNAL OF NEURAL SYSTEMS. World Scientific Publishing Co. 2017, Vol. 27, Issue 1.
  5. Zarei Eskikand P, Kameneva T, Ibbotson M, Burkitt A, Grayden D. A Possible Role for End-Stopped V1 Neurons in the Perception of Motion: A Computational Model. PLOS ONE. Public Library of Science. 2016, Vol. 11, Issue 10.
  6. Maturana M, Apollo N, Hadjinicolaou AE, Garrett D, Cloherty S, Kameneva T, Grayden D, Ibbotson M, Meffin H. A Simple and Accurate Model to Predict Responses to Multi-electrode Stimulation in the Retina. PLOS COMPUTATIONAL BIOLOGY. Public Library of Science. 2016, Vol. 12, Issue 4.
  7. Saha S, Greferath U, Vessey K, Grayden D, Burkitt A, Fletcher E. CHANGES IN GANGLION CELLS DURING RETINAL DEGENERATION. NEUROSCIENCE. Pergamon-Elsevier Science. 2016, Vol. 329.
  8. Opie N, John S, Rind G, Ronayne S, Grayden D, Burkitt A, May C, O'Brien T, Oxley T. Chronic impedance spectroscopy of an endovascular stent-electrode array. JOURNAL OF NEURAL ENGINEERING. Institute of Physics Publishing. 2016, Vol. 13, Issue 4.
  9. Opie N, Rind G, John S, Ronayne S, Grayden D, Burkitt A, May C, O'Brien T, Oxley T. Feasibility of a chronic, minimally invasive endovascular neural interface. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. Institute of Electrical and Electronics Engineers. 2016, Vol. 2016-October.
  10. Cook M, Freestone D, Himes D, Leyde K, Berkovic S, O'Brien T, Grayden D, Boston R. Human focal seizures are characterized by populations of fixed duration and interval. EPILEPSIA. Blackwell Science. 2016, Vol. 57, Issue 3.
  11. Freestone D, Boston R, Grayden D, Himes D, Leyde K, Seneviratne U, Berkovic S, O'Brien T, Cook M. Interictal spikes and epileptic seizures: their relationship and underlying rhythmicity. BRAIN. Oxford University Press. 2016, Vol. 139, Issue 4.
  12. Erfanian Saeedi N, Blamey P, Burkitt A, Grayden D. Learning Pitch with STDP: A Computational Model of Place and Temporal Pitch Perception Using Spiking Neural Networks. PLOS COMPUTATIONAL BIOLOGY. Public Library of Science. 2016, Vol. 12, Issue 4.
  13. Oxley T, Opie N, John S, Rind G, Ronayne S, Wheeler TL, Judy JW, McDonald A, Dornom A, Lovell T, Steward C, Garrett D, Moffat B, Lui E, Yassi N, Campbell B, Wong Y, Fox KE, Nurse E, Bennett I, Bauquier S, Liyanage K, Van Der Nagel NR, Perucca P, Ahnood A, Gill K, Yan B, Churilov L, French C, Desmond P, Horne M, Kiers L, Prawer S, Burkitt A, Grayden D, May C, O'Brien T. Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity. NATURE BIOTECHNOLOGY. Nature Publishing Group. 2016, Vol. 34, Issue 3.
  14. Ahmadizadeh S, Nesic D, Freestone D, Grayden D. On synchronization of networks of Wilson-Cowan oscillators with diffusive coupling. AUTOMATICA. Pergamon-Elsevier Science. 2016, Vol. 71.
  15. Kameneva T, Maturana M, Hadjinicolaou AE, Cloherty S, Ibbotson M, Grayden D, Burkitt A, Meffin H. Retinal ganglion cells: mechanisms underlying depolarization block and differential responses to high frequency electrical stimulation of ON and OFF cells. JOURNAL OF NEURAL ENGINEERING. Institute of Physics Publishing. 2016, Vol. 13, Issue 1.

David Grayden

Level: 02 Room: 229
Electrical and Electronic Engineering, Parkville
University of Melbourne
3010 Australia

T: +61 3 90353796
F: +61 3 83447422

View a full list of publications on the University of Melbourne’s ‘Find An Expert’ profile