Professor David Grayden

Research Interests

  • Bionic Ear (Speech processing, bionics, neuroengineering)
  • Bionic Eye (Vision processing, bionics, neuroengineering)
  • Brain-Machine Interfaces (Brain-computer interfaces, bionics, neuroengineering)
  • Computational Neuroscience (Neural modelling, neural learning, neural dynamics, neuroengineering)
  • Epilepsy (Prediction of seizures, seizure control, neuroengineering)

Personal webpage


Professor David Grayden is in the Department of Electrical and Electronic Engineering at The University of Melbourne.

Prof Grayden is Director of Biomedical Engineering, Director of the NeuroEngineering Laboratory in Electrical & Electronic Engineering, and Leader of the Bionics Laboratory in the Centre for Neural Engineering.

Prof Grayden's main research interests are in understanding how the brain processes information, how best to present information to the brain using medical bionics, such as the bionic ear and bionic eye, and how to record information from the brain, such as for brain-machine interfaces. He is also conducting research in epileptic seizure prediction and electrical stimulation to prevent or stop epileptic seizures. He has research linkages in Australia with Cochlear Limited, the Bionics Institute, St Vincent's Hospital Melbourne, Royal Melbourne Hospital, NICTA, University of South Australia, Florey Institute for Neuroscience and Mental Health.  He also has international research linkages with TU Illmenau (Illmenau University of Technology) and McMaster University.  He supervises a number of postdoctoral researchers and PhD and Research Masters students.

Prof Grayden teaches in the Bioengineering and Biomedical Engineering programs.  He teaches in the subjects: Neural Information Processing, Biosystems Design, and Biomedical Engineering Design Project.  He also contributes to the Neuroscience Research Training course modules.

Research interests:
Computational Neuroscience
Audition, Speech and Bionic Ear Design
Vision and Bionic Eye Design
Brain-Machine Interfaces

Recent Publications

  1. Spencer M, Nayagam D, Clarey JC, Paolini A, Meffin H, Burkitt A, Grayden D. Broadband Onset Inhibition Can Suppress Spectral Splatter in the Auditory Brainstem. PLOS ONE. Public Library of Science. 2015, Vol. 10, Issue 5.
  2. Kuhlmann L, Grayden D, Wendling F, Schiff SJ. Role of multiple-scale modeling of epilepsy in seizure forecasting. Journal of Clinical Neurophysiology. Lippincott Williams & Wilkins. 2015, Vol. 32, Issue 3.
  3. Kameneva T, Abramian M, Zarelli D, Nesic D, Burkitt AN, Meffin H, Grayden D. Spike history neural response model. JOURNAL OF COMPUTATIONAL NEUROSCIENCE. Kluwer Academic Publishers. 2015, Vol. 38, Issue 3.
  4. Kameneva T, Zarelli D, Nesic D, Grayden D, Burkitt A, Meffin H. A comparison of open-loop and closed-loop stimulation strategies to control excitation of retinal ganglion cells. Biomedical Signal Processing and Control. Elsevier Science. 2014, Vol. 14.
  5. Erfanian Saeedi N, Blamey P, Burkitt A, Grayden D. Application of a pitch perception model to investigate the effect of stimulation field spread on the pitch ranking abilities of cochlear implant recipients. Hearing Research. Elsevier Science. 2014, Vol. 316.
  6. Kuhlmann L, Hauser-Raspe M, Manton J, Grayden D, Tapson J, Van Schaik A. Approximate, Computationally Efficient Online Learning in Bayesian Spiking Neurons. Neural Computation. MIT Press. 2014, Vol. 26, Issue 3.
  7. Kerr R, Grayden D, Thomas D, Gilson M, Burkitt A. Coexistence of Reward and Unsupervised Learning During the Operant Conditioning of Neural Firing Rates. PLoS One. Public Library of Science. 2014, Vol. 9, Issue 1.
  8. Wong RCS, Garrett D, Grayden D, Ibbotson M, Cloherty S. Efficacy of Electrical Stimulation of Retinal Ganglion Cells with Temporal Patterns Resembling Light-Evoked Spike Trains. 2014 36TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC). IEEE. 2014.
  9. Monfared O, Nesic D, Freestone D, Grayden D, Tahayori B, Meffin H. Electrical Stimulation of Neural Tissue Modeled as a Cellular Composite: Point Source Electrode in an Isotropic Tissue. International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE Press. 2014.
  10. McLachlan N, Grayden D. Enhancement of speech perception in noise by periodicity processing: A neurobiological model and signal processing algorithm. Speech Communication. North-Holland. 2014, Vol. 57.
  11. Freestone D, Karoly P, Nesic D, Aram P, Cook M, Grayden D. Estimation of effective connectivity via data-driven neural modeling. FRONTIERS IN NEUROSCIENCE. Frontiers Research Foundation. 2014, Vol. 8.
  12. Liang X, Kuhlmann L, Johnston L, Grayden D, Vogrin S, Crossley R, Fuller K, Lourensz M, Cook M. Extending Communication for Patients with Disorders of Consciousness. Journal of Neuroimaging. Sage Science Press. 2014, Vol. 24, Issue 1.
  13. Kameneva T, Grayden D, Meffin H, Burkitt A. Feedback stimulation strategy: control of retinal ganglion cells activation. International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE Press. 2014.
  14. Kerr R, Grayden D, Thomas D, Gilson M, Burkitt A. Goal-directed control with cortical units that are gated by both top-down feedback and oscillatory coherence. FRONTIERS IN NEURAL CIRCUITS. Frontiers Research Foundation. 2014, Vol. 8.
  15. Kiral-Kornek F, O'Sullivan-Greene E, Savage CO, McCarthy C, Grayden D, Burkitt A. Improved visual performance in letter perception through edge orientation encoding in a retinal prosthesis simulation. Journal of Neural Engineering. Institute of Physics Publishing. 2014, Vol. 11.

David Grayden

Level: 02 Room: 228
Electrical and Electronic Engineering, Parkville
University of Melbourne
3010 Australia

T: +61 3 90353796
F: +61 3 83447422

View a full list of publications on the University of Melbourne’s ‘Find An Expert’ profile